How to get rich

October 24, 2013 • 12:00 pm

Build your own bestseller: three idiot-proof formulas” by Noreen Malone at The New Republic‘s site.

But there’s a better way, actually. Just have a near-death experience, pretend you went to heaven and saw Jesus, leaven the narrative with some juicy details about what heaven is like (How tall is Jesus? Are there cats up there? What do they eat?), and you’re golden.  There’s nothing the public likes better than Proof of Heaven.

Picture 5 Picture 4

Picture 6

Questions for compatibilists

October 24, 2013 • 9:08 am

A long time ago, everyone thought bachelors were unmarried and that it was wrong for a married man, but not a bachelor, to have sex with multiple people.  Then a philosopher got the bright idea of redefining “bachelor” to include “those married men who didn’t have much sex with their wives.”  That redefinition allowed some married men to think of themselves as free to pursue other women. They were happier.

Although it’s a stretch, something like this seems to me to parallel what has happened with the rise of “compatibilism.” That is the notion that although the universe may be deterministic in a physical way—so that our actions and thoughts are not only determined by the laws of physics, but also predictable if we had enough foreknowledge—we nevertheless have “free will.”  What philosophers did was redefine the meaning of “free will” away from its historical and religious sense, so that “free”, instead of meaning “independent of the strictures of your bodily makeup and environmental influences”, now meant a variety of other things, like, “your decision isn’t being made with a gun to your head.”

There is no one form of compatibilism: various philosophers have suggested various tweaks that allow us to say we have “free will.”

To me, the important aspect of this debate came not from philosophy but from science: we realized that our brains, like all physical objects, are subject to the laws of physics, and there was no way that some nonmaterial spook in one’s head could make “free decisions”. That was something new.

The idea of a deterministic universe, we all agree, was an important one, and so we can conceive of humans as immensely complicated and evolved machines.  That does not mean, of course, that we know exactly how they will behave, for determinism does not equal predictability—unless we have perfect knowledge.

So determinism, and its view that the mind is what the brain does, was a tremendous advance in science. And it completely dispelled the notion of dualistic free will. Here are the questions, then, that I have for compatibilists.

What kind of comparable advance was achieved by redefining “free will” so that the only thing “free” about it was its freedom to accept determinism?

Has compatibilism had an important (or might have a potentially important) influence on humanity or its behavior?

Is compatibilism anything more than a semantic gesture?

How has compatibilism helped us understand the human brain or human behavior?

I see compatibilism as a branch of philosophy, and determinism as something that is largely scientific but has philosophical implications. And—I won’t pull any punches here—I don’t think compatibilism is of any importance to humanity.

Now when I say that “compatibilism was confected to allow humans to have free will and avoid the notion that we’re automatons,” I’m pretty serious. In response, people tell me that “compatibilism has a long and distinguished history,” and was not a response to determinism.

I’m not convinced about that, because determinism itself has a long and distinguished history.  Here are two examples:

Spinoza (in Ethics): ″the infant believes that it is by free will that it seeks the breast; the angry boy believes that by free will he wishes vengeance; the timid man thinks it is with free will he seeks flight; the drunkard believes that by a free command of his mind he speaks the things which when sober he wishes he had left unsaid. … All believe that they speak by a free command of the mind, whilst, in truth, they have no power to restrain the impulse which they have to speak.″

Laplace: “We ought to regard the present state of the universe as the effect of its antecedent state and as the cause of the state that is to follow. An intelligence knowing all the forces acting in nature at a given instant, as well as the momentary positions of all things in the universe, would be able to comprehend in one single formula the motions of the largest bodies as well as the lightest atoms in the world, provided that its intellect were sufficiently powerful to subject all data to analysis; to it nothing would be uncertain, the future as well as the past would be present to its eyes. The perfection that the human mind has been able to give to astronomy affords but a feeble outline of such an intelligence.”

Since determinism has been around for a long time, it’s not inconceivable that compatibilism did arise to counteract determinism, and make us feel that we really did have free agency.

But, ignoring that, I still want to know why compatibilism is considered a serious achievement in philosophy. Contrary to determinism, which does have serious implications for how we live our lives and run our societies, compatibilism is an arcane backwater of philosophy. It is not a philosophical achievement on the order of, say, Singer’s arguments for animal rights, which have real practical consequences, or Rawls’s musings on justice, which makes us rethink how we conceive of fairness and people’s rights.  I see no practical consequences of compatibilism save soothing the distress of people who, upon finally grasping determinism, get distressed that they are puppets on the strings of physical laws.

Which is pretty much how it is.

The first venomous crustacean is found

October 24, 2013 • 5:37 am

The phylum Arthropoda contains four major living groups, usually considered subphyla: Hexapoda (insects and a few other groups like springtails), Myriapoda (mostly centipedes and millipedes), Chelicerata (spiders, scorpions, horseshoe crabs, mites, etc.) and Crustacea (crabs, lobsters, barnacles, shrimp, etc.). Trilobites, which are extinct, are classed as another subphylum.

The first three of these living groups all contain species that have venom, which, biologically, are toxins injected into a prey with a bite or sting (delivery via those methods distinguishes venoms from, say “poisons,” as found in some frogs that are toxic to predators). Up to now, though, no crustaceans had been known to have venom.

This has changed with the publication of a new paper in Molecular Biology and Evolution (advance online manuscript; free), by Björn von Reumont et al. The authors show—not definitively, but suggestively—that some remipedes—rare, blind crustaceans that live in marine underwater caves—have venom that they inject into their prey.

Remipedes were discovered only in 1981, and there are only 17 known species. They constitute a class in the subphylum Crustacea. Here is an individual from the University of California’s Museum of Paleontology. Remipedes are about 10-40 mm long: about half an inch to 1.5 inches:

speleon_b

Previous work had suggested that these species could be venomous, as they have biting mouthparts, but this wasn’t investigated. In fact, the going wisdom was that they fed on suspended particles.  But morphological analysis of one species from the Yucatan in Mexico showed a “highly adapted venom delivery apparatus” as well as mouthparts that could deliver venom, and lab studies showed that captive individuals of the species, Speleonectes tulumensis, could indeed capture and kill small prey.  Here are the venom glands and the paper’s caption:

Picture 2
Figure 1 – 3D reconstructions of Speleonectes tulumensis (Crustacea: Remipedia)
from high resolution SR-!CT data.
A) Ventral and B) lateral view showing the course of the venom delivery system
(VDS), (purple) and its position inside the body. C) Anterior and D) posterior view
focused on the maxillule and the muscle equipment related to the VDS.
Abbreviations: 4 seg, 4th segment; 5-7 seg, 5-7th segment; ab, abductors; ad,
adductors; am, anterior apodemal muscle; br, brain; cep, cephalon; dc, ductus; gl,
gland; mxu, maxillule; phx, pharynx; rv, reservoir; t, tentorium; vm, ventral apodemal
muscle; vnc, ventral nerve cord. Images not to scale to each other, mouthparts and
other structures are not shown.

How did they find the venom? They used “transcriptomics,” a newish way of finding the DNA (and protein) sequences of genes that are actually expressed in organisms, that is, whose DNA is converted into RNA. (Remember that a lot of DNA is “junk” that never does anything.)

The authors extracted RNA from the venom glands, sequenced those RNAs by converting them to DNAs and sequencing the latter, and then translated those DNA sequences into protein sequences (the messenger RNA’s are read into proteins). They then looked in databases for proteins corresponding to known classes of venoms.

And they found at least three types of putative venoms, with 108 different forms of those venoms. The three classes are peptidases, enzymes that dissolve protein, chitinases, which do the same for that material, found in exoskeletons, and neurotoxins.  While the authors didn’t actually isolate the venom itself, they did this indirectly by finding sequences that correspond to things known to be venoms.  It remains to be demonstrated that there actually are venoms in these species that kill prey, but the evidence is pretty strong. And the venom proteins seem most closely related to proteins found in spiders.

Here’s the species that was studied:

_70643741_70643631

While the results need confirmation (are those venoms actually used to kill?), the authors suggest that “remipedes can feed in an arachnoid manner, sucking the prey’s liquefying tissue out of its cuticle.”

So there’s your fact for the day, and be sure to drop it at the next cocktail party. “Say, did you know they found the first venomous crustacean?” is sure to bring gasps of wonder and admiration over a round of martinis.

h/t: James

______________

Björn M. von Reumont, Alexander Blanke, Sandy Richter, Fernando Alvarez, Christoph Bleidorn, and Ronald A. Jenner 2013. The first venomous crustacean revealed by transcriptomics and functional morphology: remipede venom glands express a unique toxin cocktail dominated by enzymes and a neurotoxin. Mol. Biol. Evol.: mst199v1-mst199.

Thursday: Hili Dialogue

October 24, 2013 • 3:26 am

Hili seems to be getting more philosophical as she ages:

Hili: As I, too, eliminate entities which are beyond necessity, what is the difference between me and Occam’s razor?

A: Ockham suggested more economical thinking and you are more ruthless in action.

Hili: Oh well, I’m a cat.
1385624_10201864159632971_1481371127_n
In Polish:
Hili: Jeśli ja też eliminuję zbędne byty to jaka jest różnica między mną z brzytwą Ockhama?
Ja: Ockham sugerował bardziej ekonomiczne myślenie, a ty jesteś bezwzględna w działaniu.
Hili: No tak, ale ja jestem kotem.