The Consortium for the History of Science, Technology, and Medicine has now done 13 podcasts on the history of DNA, beginning with the discovery of nucleic acids through the observation that DNA was the hereditary material (Avery et al.) and (so far) up to the structure of the double helix. As far I know, our own Dr. Cobb, very eloquent behind the microphone, has been on four of these broadcasts: #3, 4, 7 and the newest one #13, about Watson, Crick, and the double helix.
You can access the whole lot by clicking on this screenshot, or get to the individual podcasts by clicking on the screenshot below.
This podcast series illuminates the history of seminal discoveries and research through which we learned about the molecule that has been dubbed as the “secret of life” itself: DNA, or deoxyribonucleic acid.
This series progresses from the first discovery of the substance in 1869 to the late 1950s, when scientists figured out the structure of this molecule and its implications for the way in which it carries out its biological functions. Each episode features scholars and experts from different fields, including the history of science, other humanities and social sciences—such as philosophy, anthropology, sociology of science and STS—the specific areas of science pertinent to the paper being discussed, and science communication.
Click on the “Resources” tab for information for researchers as well as further readings.
Jump to:
Episode 1 on Friedrich Miescher and the discovery of nuclein
Episode 2 on Albrecht Kossel and the discovery of the building blocks of nuclein
Episode 3 on Walter Sutton and the relation between chromosomes and heredity
Episode 4 on Fred Griffith and the discovery of bacterial transformation
Episode 5 on Phoebus Levene, DNA chemistry and the tetranucleotide hypothesis
Episode 6 on William Astbury, Florence Bell and the first X-ray pictures of DNA
Episode 7 on Oswald Avery, Colin McLeod, and Maclyn McCarty and the chemical basis of bacterial transformation
Episode 8 on Maclyn McCarty, Oswald Avery and the enzymatic evidence for DNA as the transforming substance
Episode 9 on Erwin Chargaff and the evidence for non-uniformity of nucleotide base composition in DNA
Episode 10 on Harriet Ephrussi-Taylor, Rollin Hotchkiss and the demonstration of bacterial transformation as a general phenomenon
Episode 11 on Alfred Hershey, Martha Chase, and the conclusive evidence for the function of DNA as the material of heredity.
Episode 12 on Maurice Wilkins, Rosalind Franklin, their collaborators, and the data that supported the double helix model for DNA structure.
Episode 13 on James Watson, Francis Crick, and the DNA Double Helix.
You can hear the latest episode, 62 minutes long, by clicking at the screenshot below, is described comme ça:
Rounding out the story begun in the previous installment, episode 13 of the DNA Papers centers on the publications in which the double helical structure for DNA was proposed, detailed, and its various implications speculated upon. It features four papers, all by Watson and Crick from Cambridge. Together these papers not only proposed that DNA’s three dimensional structure was a double-stranded helix, but also described the antiparallel and complementary nature of its two component strands and the specific pairing of the component nucleotide bases, namely, the purines, A and G, with the pyrimidines T and C respectively. The papers also discussed the implications of these features for the fundamental functions of DNA. . . .
And the participants are:
Soraya de Chadarevian, University of California, Los Angeles
Matthew Cobb, University of Manchester
Nathaniel Comfort, Johns Hopkins University
Georgina Ferry
+1
Thank you. I will look forwarding to listening to this series.
I’m late to this post – will try to catch the episodes when I have some quiet to myself in the evenings.