A scan of my brain (it’s pretty normal!)

June 26, 2016 • 1:30 pm

When I was in Los Angeles a week ago, I found myself hanging around some neuroscientists and neuropsychologists, and they persuaded me to have my brain scanned and analyzed: a “QEEG”. I had no idea what it involved, but it was completely painless. I simply donned this funny-looking hat that had 19 recording electrodes. The electrodes picked up electrical impulses from different parts of the brain, and those impulses can be combined and crunched to triangulate the activity of deeper parts of the brain.

I had no idea what I was getting into, but the 60-minute procedure, combined with a computer program that analyzed my brain waves, produced a lot of information.  I should add that this procedure is often done by therapists as well as physicians, and can cost from $500 to several thousand dollars depending on they type of QEEG done. My procedure would have cost $1,000, so I was pleased to get a freebie. But I was also scared that I would find out my brain was abnormal!

The spike is not part of the apparatus, nor does it connote that I’m a pointy-headed intellectual:
My brain scan
Dr. Orli Peter, who is both a clinical and a neuropsychologist with a practice in Beverly Hills, explained the analysis to me:
There are several types of QEEG analyses and we use SKIL – an advanced analysis program developed by UCLA professor Barry Sterman, a pioneer in research for clinical applications for neurofeedback and his then graduate student, David Kaiser.
She and David Kaiser are colleagues in her practice and he did my actual brain scan and analyzed my brain activity using the program he helped develop.
I did the scan four ways. Two traditional ways: with my eyes closed and then with my eyes open, looking at a fixed image (a chair). And then two new ways, called the “Peter Test,” to pick up any unresolved alteration in brain functioning due to exposure to psychological trauma. “Trauma neuromarkers” have been identified via various neuroimaging techniques.

The analysis of David and Orli, summarized by the latter; I’ve put the take-home message in bold:

Just so you know, Brodmann area theta unity is analyzed in SKIL brainmapping. It is a measure of corticolimbic connectivity, an indirect measure of myelination and distribution of sub-cortically driven theta associated with cerebral maturation.

Nearly all regions in your brain show mature integration of limbic and cortical functioning. Your sensory sampling speed is at the slightly faster end of the speed shared with the majority of people, and consistent across regions, which is an indicator of healthy sensorimotor development . However, your frontal lobe shows excessive theta similarity, an indicator of primal (unmodulated) functioning in bilateral BA9 and BA47, and there is less theta similarity of the ACC and Broca’s areas, an indicator of inefficiency in functions served by these areas.

Here is a list of the the type of functioning these regions are involved with.

BA 9 —hyperlimbic connectivity may impact cognitive flexibility and planning, being able to infer the intention of others, and empathy. Children who show poor attachment have poorer activation here. Recent studies have also shown this region is involved in social fairness, and excessive limbic functioning will result in a different sense of social justice than the dominant group.

BA 47 –more primal functioning in this region may reduce decision making and (again) being able to infer the intention of others, and to properly understand emotion (this hub has been shown to specifically relate to understanding emotion when communicated through prosody.)

Anterior Cingulate Cortex (ACC) — the ACC is a major hub that has connections to both the “emotional” limbic system and the “cognitive” prefrontal cortex. Poorer integration of the ACC is associated with poorer decision making because of increased difficulty in holding two conflicting ideas simultaneously and because of poorer error detection. Poorer connectivity is also associated with poorer emotional awareness and recognition of emotional cues.

Broca’s area is associated with sequencing and hierarchical categorization, a subset that influences language.

In sum, the overall view is that most regions of your brain are functioning very well, better than most, but your ability to make decisions, infer intention of others, understand emotion and share in perceptions of social justice is driven by more limbic processes, making behaviors that rely on these abilities more challenging or unique.

I take this to mean that I have the moral sense and the empathy of an early mammal!

The type of corticolimbic integration are converted into colors, and, I was told, the more green your brain areas are, the more “normal.”. I was largely green, which greatly relieved me:

Brodmann Overview - BA Exec jchec50

Re The Peter Test: I did not show any alteration in the functioning of my default-mode-network due to psychological trauma. In other words, there is no sign that I’ve been traumatized (this could either mean “never traumatized” or “traumatized and recovered from it”) which jibes pretty well with my own self-assessment.  

And here’s my list of sampling rates from the 19 electrodes. The explanation, from Orli, is below. Of course most of it is beyond me, but I’m sure some readers will understand:

Dominant Frequency1-jerry

Re the chart above:
Sampling rates are shown two ways: dominant frequency table at 1/8 hz sensitivity and as spectral entropy plots which are 1 hz sensitivity. The “overall” is peak from 1 to 45 hz and can be ignored. This range will show artifact and delta and pink noise peaks. The sensory information gating peak is typically between 7-14 hz which is the second column and one to pay attention to. This information is also represented in spectral entropy plots. Here we can see the organization of frequency activity for each brain region (see first figure above).
 The peak frequency around 10.75 hz in much of your regions is calculated by tallying up frequency bins across recording. In the “eyes closed” condition typically we will see sinusoidal activity, and this is the primary speed of these sinusoidal waveforms. These waveform are generated by the thalamocortical loop and are the rate of inhibition by the reticular thalamic nuclei which sheaths most of the thalamus and is this inhibition is activated mostly by thalamus on the thalamic relay to cortex of sensory information  when there is little or no sensory stimulation the thalamus goes into an idling speed and this is the relaxed rate of sensory volleying to cortex; i.e., our relaxed or default sensory sampling rate of environment. This is not our max rate- just our default; We can sample and gate information to the cortex faster or slower than this, depending on the situation.
I was grateful to get this analysis for free, and relieved that I’m not some kind of brain freak! If you’re in LA or traveling there, you can contact this email to get an appointment for your own SKIL EEG. Dr. Peter gives discounts to those who can verify financial need; and insurance can cover some of the cost as well.

Gun control: did it reduce suicides and homicides in Australia?

June 26, 2016 • 12:15 pm

I keep calling for more stringent gun laws in the U.S.; in fact, I would, if I were in charge, take the U.S. to the British system, in which private ownership of handguns is prohibited and rifles can be owned only for sports shooting or hunting—and under strict licensing. In contrast, many gun advocates say that the U.S. would become more dangerous should such legislation be enacted, and, regardless, the Second Amendment guarantees us private ownership of guns (the Supreme Court agrees; I don’t).

There is one “natural” experiment in banning guns: that in Australia, where, after mass shootings, stringent gun control was imposed in 1996. (Actually, the UK did another, but I know of no data like what I’ll show below.) And the data on homicides and suicides for periods of roughly two decades before and after the ban has just been analyzed and published in the Journal of the American Medical Association by Simon Chapman et al. (reference and free download below).  The upshot is that there are some data suggesting that gun-related suicides and homicides decreased after the ban, but in some cases it didn’t reach statistical significance.

There are two problems here. First, firearm-related homicides and suicides were already decreasing before the gun ban, so the analysis had to determine whether the rate of decline of gun-related deaths increased after the gun ban, and that method involves estimating regression coefficients—an insensitive way to detect anything other than big changes in rate.

Second, there may have been other changes over time that decreased gun-related deaths after the ban, namely the wider use of cellphones, which allow one to report shootings faster, possibly saving more lives and thus reducing the homicide rates, as well as improvements in medical care, so a suicide or shooting is less likely to cause death. Since the data analyzed involve only deaths and not injuries, the authors can’t rule out these factors.

That said, the data show that the number of mass shootings (defined as shootings in which more then five people die) dropped to zero after the ban (19 years after the gun ban was enacted), while there were 13 such incidents in the 18 years before the gun ban was enacted. That itself is a significant difference if you use a simple two-sample chi-square test assuming equality of numbers, but that difference may reflect only the same trend of reduced homicides over time. However, the overall data show that in every case the rate of decline in gun-related deaths increased after the ban, and didn’t increase in any case, as the gun-lovers would have us believe. Moreover, in some cases the faster decline was statistically significant.  The report then, is heartening but not decisive. It certainly gives us no cause to think that if a Western nation suddenly tightened its gun policies, gun-related deaths would rise.

First, the facts (all quotes from the paper):

In 1996, Australia’s state and federal governments introduced sweeping uniform gun laws that were progressively implemented in all 6 states and 2 territories between June 1996 and August 1998. The enactment of these laws followed a massacre on April 28, 1996, in which a man used 2 semiautomatic rifles to kill 35 people and wound 19 others. The new gun laws banned rapid-fire long guns (including those already in private ownership), explicitly to reduce their availability for mass shootings.

In addition, by January 1, 1997, all 8 governments commenced a mandatory buyback at market price of prohibited firearms. As of August 2001, 659 940 newly prohibited semiautomatic and pump-action rifles and shotguns had been purchased by the federal government from their civilian owners at market value, funded by a one-off levy on income tax, and destroyed.  From October 1, 1997, large criminal penalties, including imprisonment and heavy fines, applied to possession of any prohibited weapon.

During a second firearm buyback in 2003, 68 727 handguns were collected and destroyed. Thousands of gun owners also voluntarily surrendered additional, nonprohibited firearms without compensation, and since 1996 thousands more privately owned firearms are known to have been surrendered, seized, and melted down.

The trends. The authors looked at overall suicide and homicide fatalities, and then separated them into those involving guns and those not involving guns. (They also gave separate and combined data for suicides and homicides.) I’ll show the trends only for the data separated by whether or not they involved firearms, leaving out the combined (firearm + nonfirearm) deaths:

joi160074f1

You can see that both suicides and homicides involving firearms were already decreasing before the ban (vertical line), while suicides and homicides not involving firearms were either increasing or steady. In the latter case, though, both kinds of deaths decreased after the gun ban, suggesting that better medical care, increased cellphone use, or other factors were involved.

Here are the statistical analyses:

joi160074t3

The column to look at is the P values in the RT column (ratio of trends happening before and after gun control; “RL” looks for a step change occurring in 1996). You can see that in every case (5 out of 5 non”total” cases involving separated firearm and nonfirearm deaths: rows 2-4 and 6-7 in Table 3), the death rates declined more steeply after than before gun laws. That alone is nearly statistically significant, but remember that two of these statistics are deaths not involving firearms. In one analysis of firearm deaths—suicide—the drop was significantly steeper after 1996, and for all homicides it was almost significant (p = 0.06). But the drops in non-firearm deaths also accelerated after 1996, which again may reflect other factors (including, in the case of suicide, better prevention techniques).

Largely because of the contribution from fewer suicides, the rate of decrease in total firearm deaths, involving both suicides and non-suicides, was larger after gun control than before. All of this shows that easy access to firearms, at least in Australia, seemed to promote more suicides than homicides.

What’s the lesson? As I said, it’s a bit problematic because of other factors, factors that could be reflected in a decrease in nonfirearm deaths as well. Nevertheless, there are no data here suggesting that firearm deaths will increase after guns are largely banned. In other words, these data show that such a ban is worth trying, as there appears to be no downside.

Ideally, we’d want more data from other countries, but we can’t get it from the one country everyone’s concerned about: the U.S. Until the Supreme Court interprets the Second Amendment correctly, and the legislature gets the moxie to buck the National Rifle Association and enact meaningful gun laws, we simply won’t know what will happen in the U.S. if we followed Australia’s lead. The data above, however, suggest that we should.

________

Chapman, S., P. Alpers, and M. Jones. 2016. Association between gun law reforms and intentional firearm deaths in Australia, 1979-2013. J. Am. Medical Association. doi:10.1001/jama.2016.8752 Published online June 22, 2016.

My podcast with Hemant Mehta

June 26, 2016 • 9:00 am

Hemant Mehta, the “Friendly Atheist“, waylaid me during the American Humanist Association meetings (he lives in “Chicagoland”) and asked me to do a podcast with him. I readily agreed, as he’s a nice guy, and the podcast, in which I was co-interviewed by Hemant and Jessica Bluemke, was just posted. You can find it by clicking on the screenshot. As always, I can’t bear to listen to these things, but I do remember I made up a Dr. Seuss-like poem on the spot about Regressive Leftism. I don’t know if it made the final cut.

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Readers’ wildlife photos

June 26, 2016 • 7:30 am

Brigette Zacharczenko is a graduate student in the Department of Ecology and Evolution at the University of Connecticut, Storrs, working on the evolution of moths. Her other interests include biological illustration, keeping a menagerie of pets that few people would want around, powerlifting, making lovely plush animals (I want a tardigrade!), and coordinating events during National Moth Week. Beside the horseshoe crabs that are today’s main subject, I also found a video she sent me in 2014, which I don’t think I’ve posted.

First, the crabs, sent June 22 along with Brigette’s commentary. Note: horseshoe crabs—the ones below are the famous blue-blooded Limulus polyphemus—aren’t really crabs. While both groups are arthropods, horseshoe crabs are in the subphylum Chelicerata along with scorpions and spiders. “Real” crabs, on the other hand, are in the subphylum Crustacea. That means, of course, that the animals you see below are more closely related to spiders than to the crabs we eat.

Hello! I’m a long time reader and I thought you might enjoy these photos I took last night. My friends and I went to Napatree Point in Rhode Island hoping to see some mating horseshoe crabs (they typically mate during the full moon). It wasn’t the piles of chelicerates on the sand like you see in some photos, but we did see hundreds in the water by the shore! I remembered seeing some pictures of them glowing under UV lighting, so I brought a little handheld UV flashlight. As far as I can tell, no one is quite sure why they glow – or perhaps there is no reason at all, and it is a byproduct of how their exoskeletons are constructed? We did notice a lot of individual variation in the extent of their fluorescence, typically the fresher looking ones (recently molted, not covered in barnacles and limpets) would pop bright green.

We also got to follow the volunteers of “Project Limulus” as they were counting individuals, measuring body widths, and recording tags. Overall, it was a magical night.

These are from my phone, so I apologize for their size/dimensions.

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Just to show you how big these mating aggregations can be, here’s a photo of individuals on Long Island Sound, courtesy of WNPR and the U.S. Fish and Wildlife Service:

US_Fish_and_Wildlife_Service

If you want to learn more about horseshoe crabs, here’s a 50-minute documentary from WildOcean:

Finally, I found a video that Brigette made and sent me in 2014:
A student brought a caterpillar (Euchaetes egle) into my office, wondering if the caterpillar was still alive. It certainly was moving, but not for usual reasons.

The resident parasitoid had eaten the caterpillar, became restless, and decided to take a hike, perhaps to pupate. It is a fly maggot in the family Tachinidae. They commonly target caterpillars.

I took the video with my phone, at first only hoping to record the wiggling motions of the caterpillar. I was quite surprised when the parasitoid fully emerged!

That reminded me of the botfly that emerged from my head.

Sadly, these are no longer available:

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Sunday: Hili dialogue

June 26, 2016 • 6:30 am

It’s going to be another scorcher in Chicago today, with high temperatures about 87° F (31° C) with even hotter weather tomorrow. It’s June 26, 2016, and Brisbane, Australia is having a weeklong celebration (photo courtesy of Dr. Michael Turelli, who’s visiting the city):

IMG_0462

On this day in 1907, the Tiflis bank robbery, organized by Lenin, Stalin, and their confederates to fund the Bolsheviks, took place, killing 40 people and netting the Reds several million dollars in today’s currency. In 1963, John F. Kennedy gave his “Ich bin ein Berliner” speech. I’ve been told that saying “ein Berliner” rather than “Berliner” makes it mean “I am a jelly donut,” but that appears to be wrong. On June 26, 1974, the Universal Product Code was used for the first time, scanning a pack of chewing gum at a supermarket in Ohio. And, in 2015, the U. S. Supreme Court ruled that gay couples have a right to marry.

Notables born on this day include Chesty Puller (1898), Babe Didrikson Zaharias (1911), Chris Isaak (1956), and Derek Jeter (1974). Those who died on this day include Malcolm Lowry (1957), Roy Campanella (1993), and the wonderful Nora Ephron (2012). Meanwhile in Dobrzyn, Hili is again looking for avian noms:

Hili: I have to go to confession.
A: Why?
Hili: I’ve sinned against my flying bretheren again.
P1040446

In Polish:

Hili: Muszę iść do spowiedzi.
Ja: Dlaczego?
Hili: Znowu zgrzeszyłam wobec fruwających braci.

Meanwhile, at Ten Cats, the search continues for a bellhop for Cat’s Inn:

tc160621

And the cat shall lie down with the rodent. . .

George Will leaves the Republican Party (guess why?)

June 25, 2016 • 3:15 pm

I have to hand it to George Will: he seems to be getting more sensible as he gets older. Two years ago he gave up his self-declared status as a “none” (he used to be very sympathetic to faith) and declared himself a flat-out atheist, and then, in December he took a strong pro-science stand:

Higher education is increasingly a house divided. In the sciences and even the humanities, actual scholars maintain the high standards of their noble calling. But in the humanities, especially, and elsewhere, faux scholars representing specious disciplines exploit academia as a jobs program for otherwise unemployable propagandists hostile to freedom of expression.

He’s also not wearing bow ties as often: a good move.  Nobody looks good in a bow tie (are you listening, Science Guy?).

Now, according to CNN, Will is leaving the G.O.P. because he can’t stomach Donald Trump:

Conservative commentator and columnist George Will says he is leaving the Republican Party because of Donald Trump — and he’s advocating that others do the same.

In a speech at a Federalist Society luncheon Friday, he told the audience, “This is not my party,” according to PJ Media, a conservative media blog.

The Pulitzer Prize winner told the audience at the luncheon that House Speaker Paul Ryan’s endorsement of Trump is one of the reasons why he decided to leave the party, and he didn’t say whether he’d vote for either Democratic presumptive nominee Hillary Clinton or a third-party candidate, such as Libertarian Gary Johnson.

Will, who worked on President Ronald Reagan’s 1980 campaign, also said at the luncheon that Trump as president with “no opposition” from a Republican-led Congress would be worse than Clinton as president with a Republican-led Congress. When asked by PJ Media about his message to conservatives, Will responded on Trump, “Make sure he loses. Grit their teeth for four years and win the White House.”

A few of my friends are now all wonky about Trump, saying that the Brexit vote in Europe makes it more likely that The Donald will win the Presidency in November (see Amy Davidson’s alarums in The New Yorker), but I’m not worried.

bigwill_0