Yesterday I wrote a brief report on the death of J. D. Watson, who left this earthly vale at age 97. You can read the NYT obituary for him, which is quite good (archived here), so I’ll just describe my two encounters with the man, one of which was quite funny. The encounters are in fact loosely related.
Watson got his B.S. at the University of Chicago in 1947, and since he was born here (and presumably had relatives here), he would come back to the University on some Alumni Days. On those days the science labs throughout the University would set up demonstrations of what they were doing. Building doors were unlocked to allow alumni to wander in at will and get educated about science.
One of the demonstrations was on the first floor of my building: the Zoology Building, which was a going group of labs and lecture halls even in Watson’s Day. A postdoc in Marty Kreitman’s lab named John McDonald, now a professor at the University of Delaware, was demonstrating how DNA was sequenced. John had set up a PCR machine and was also running amplified DNA on a gel to show how it was sequenced.
It was the weekend, and I was down in the first-floor lab shooting the breeze with John, who was doing his demonstration although nobody else was there. All of a sudden J. D. Watson strolled into the lab! I was flabbergasted! I knew of course what he looked like, but apparently John did not. Watson asked John what he was doing, and John proceeded to explain to Mr. DNA what DNA was and how it was sequenced. I remember John taking a very elementary approach, telling Watson, “I’m sequencing DNA. Do you know what DNA is?” Watson stood there, saying nothing but listening intently. John proceeded to tell Watson what DNA was, using a simile like, “Well, imagine a string with four colored beads on it. Each of those beads is a nucleotide base, and pairs specifically with a bead of another color. . ” And so on and so on. . . I was flabbergasted.
At this point my jaw was on the floor as McDonald, completely unaware of whom he was explaining stuff to, went through the whole megillah of DNA pairing, PCR amplification, sequencing, and so on. Watson stood there paying rapt attention the whole time.
After John’s explanation. Watson thanked him and wandered out of the building. As soon as he’d gone, I said to John, very loudly, “DO YOU KNOW WHO THAT WAS?” John said “no”. So I told him he’d just explained DNA at great length to the man who helped determine its structure. McDonald, of Irish descent, freckled and with copper hair, was so embarrassed that he turned about as red as a human being could get. And there were only two witnesses to this funny tale.
Watson was very polite, and in the end John ‘s explanation had a great outcome. It turned out that Watson was so impressed that a postdoc was willing to explain DNA sequencing in such detail, and to a total stranger, that Watson donated a large sum of money to our department, intended to create a series of lectures—”The Jean Watson Lectures,” in honor of JDW’s beloved mom—that were to deal with evolution and DNA. This series went on for many years, but now it’s gone,.
This brings us to my second encounter with Watson. He was here for one of the annual lectures, for he introduced the lecture’s own introducer, saying a bit about his mother and his undergraduate years at Chicago. The department members were given a chance to have individual appointments with Watson, and I grabbed one. (Because the accusations of racism against Watson had already begun then, not a lot of people wanted to talk to him. He was also known to be daunting.) So I got a 45-minute appointment with Watson, and, in fact, it was doubled, because the person after me didn’t show up. So I had an hour and a half to occupy JDW, which I considered a great chance to chat despite his demonization for racism (yes, the conversation showed that he was a bit of a bigot). That’s where this photo came from (it was on May 29, 2012):

I don’t remember everything we talked about, though I do remember that Watson spent a lot of time complaining about how his characterization as a racist was unfair. (See the section called “Public remarks on genetics, intelligence, and race” in his Wikipedia bio for the accusations.) His bigoted words ultimately led to his suspension as head of the Cold Spring Harbor Labs, and, after an illustrious career, would have affected him greatly. Truth be told, I did see signs of bigotry in Watson during the conversation, but for the life of me I can’t remember what he said about that.
I do remember asking him—because I knew he was an atheist—if atheism or naturalism played any role in the discovery of the DNA structure. Watson said “yes”, explaining that he and especially Crick were motivated in part to find that structure because they wanted to demonstrate that the “secret of life” (i.e., the molecule that was a recipe for human beings) was a purely naturalistic phenomenon.
Yes, Watson was a difficult man, and one not free from bigotry, but we should also remember his positive accomplishments, which included not only the co-discovery of DNA’s structure; the writing of the standard book in the field The Molecular Biology of the Gene (an enormously influential book, followed by two other texts); the writing of The Double Helix, the only genetics book I know of that was a best seller (yes, it unfairly portrayed Rosalind Franklin, but Watson later apologized, and Matthew Cobb gives the best evaluation of that controversy here); setting up the Human Genome Project (this is often forgotten, but Watson resigned as head because of differences with Bernadine Healey, head of the NIH, who wanted to patent the DNA sequences, and Watson would have no part of that); and expanding and focusing the mission of the Cold Spring Harbor Laboratory. He is one of many biologists who had sides of their nature that were unpleasant, but also made great scientific contributions.
So those are my Watson stories (I’ve told the one about Alumni Day before), and will serve as my memorial to the man.
Oh, I forgot one thing. A few years earlier I was browsing in a bookstore in Boulder, Colorado, and found a first printing of The Double Helix for only five bucks. It was in great condition and I snapped it up. I didn’t think I’d ever meet Watson, but when I did I took the book along, hoping he’d autograph it. He did, and also signed several other books for me, including the one below, an annotated version of the real thing.
